KneeSim - Muscosceletal Simulation of Knee Biomechanics During Functional Tasks

Project Duration: 01.08.2024 to 30.06.2026

Degenerative musculoskeletal disorders, such as knee osteoarthritis, are on the rise worldwide. In 2020, the prevalence of knee osteoarthritis among adults over 40 ranged from 19.8% to 26.1%. In Austria, osteoarthritis is diagnosed in approximately 10.5% of men and 18.3% of women over the age of 45. Furthermore, 202 people per 100,000 inhabitants received a total knee replacement in 2019, making Austria one of the countries with the highest prevalence of this procedure. Risk factors for these conditions include a sedentary lifestyle, obesity, and poor motor control. Osteoarthritis significantly impairs activities of daily living such as walking, climbing stairs, and standing up, and often leads to a sedentary lifestyle.

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Research Areas

Digital Innovation, Engineering, and AI
Life Sciences, Health, and Quality of Life

Research Center

Research Center Digital Health and Care
Research Center Health Sciences

Department

Health Sciences

For this reason, in the SETT project we are creating a reference database on leg biomechanics for various everyday tasks and physical exercises. Knee biomechanics is of critical importance as it relates to patellofemoral and tibiofemoral joint loading, which is associated with patellofemoral pain and knee osteoarthritis. Research has identified several biomechanical factors that predispose people to patellofemoral and knee osteoarthritis, including valgus knee (knock knees), lower leg/thigh rotation, hip adduction and gluteus medius muscle activity. Understanding these factors is crucial for stabilizing the knee and reducing joint contact forces. KneeSim now aims to use musculoskeletal simulation in OpenSim to provide insight into the internal processes of the musculoskeletal system in order to identify movements with high loads.

 

Research Goals

  • Development of a musculoskeletal simulation procedure for the calculation of patellofemoral and tibiofemoral contact forces of the knee joint
  • Identification of movement types in functional exercises and activities of daily living and their relationship to joint loading
  • Creation of statistical or machine AI models to predict joint contact forces based on visually detectable kinematic data
  • Testing real-time biofeedback on joint loading in order to induce movement adaptations in healthy adults during functional exercise and activities of daily living
  • Transfer the results of musculoskeletal simulation to practical biofeedback therapy
  • Enable early detection, prevention and intervention of knee pathologies
 

Cooperation Partners


UN Sustainable Development Goals


Project Lead

Project Team