Model-Based Treatment of Thyroid Diseases

Project duration: March 2023 to February 2024

The regulation of thyroid hormones is still a young field of research, as the control cycle has yet to be fully understood. Due to the resulting complexity in determining the so-called equilibrium point (set point) for determining the individual medication dosage and the increasing number of thyroid diseases, a medical aid could shorten the treatment time. Therefore, the long-term goal is to develop a medical assistance tool based on a mathematical model. Using previous measurements, this tool is intended to formulate a medication recommendation for the respective patient in the sense of individualised medicine.

The associated lower treatment costs would not only relieve the burden on the healthcare system, but would also reduce patient suffering due to the shorter adjustment time.

Ein Modell zum Behandlungsvorgang ist abgebildet

Research objectives

Investigation/adaptation of suitable time-based mathematical models
Data validation and verification of a retrospective study conducted at Vienna General Hospital
Creation of a development concept for an assistance tool
Design of a clinical study to evaluate the app in practical use
Technical implementation after evaluation
Requirements assessment among endocrinology residents and data evaluation
Design of a validation model for a clinical study
Project evaluation