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- Fundamental features of genetics and genetic engineering

- Different levels of regulation of gene expression in pro- and eukaryotes

- Transcriptional regulation (transcription in eukaryotes, transcriptional activation, properties of transcription factors, methods for analysis of transcription factors and regulatory regions)

- Posttranscriptional regulation (splicing, transport, stability of mRNA, translational control)

- Effects of chromatin (composition, histone modifications, regulation, epigenetics)

- - Methods for analysis of genetics and gene regulation in vitro and in vivo

Lecture

Endprüfung

Written exam on the computer (multiple choice)

- Course Focus: Strategies of scientific research

- Learning Activities:

- Develop a research strategy on a specific topic in drug discovery.

- Design experiments and work packages.

- Evaluate designs based on criteria such as:

- Significance for the research question

- Costs

- Effort

- Final Task: Present the research project as a group.

Dialogue and discussion

Immanente Leistungsüberprüfung

The presentation and discussion of research projects will be evaluated.